Commander: Rick D. Husband, a US Air Force colonel and mechanical engineer, who piloted a previous shuttle during the first docking with the International Space Station (STS-96).
Pilot: William C. McCool, a US Navy commander
Payload Commander: Michael P. Anderson, a US Air Force lieutenant colonel and physicist who was in charge of the science mission.
Payload Specialist: Ilan Ramon, a colonel in the Israeli Air Force and the first Israeli astronaut.
Mission Specialist: Kalpana Chawla, an Indian-born aerospace engineer on her second space mission.
Mission Specialist: David M. Brown, a US Navy captain trained as an aviator and flight surgeon. Brown worked on a number of scientific experiments.
Mission Specialist: Laurel Clark, a US Navy captain and flight surgeon. Clark worked on a number of biological experiments.